Their demands include: stopping local-federal immigration enforcement partnerships; stopping attacks on workers and unions; halting the use of E-Verify, a federal database businesses can use to check the eligibility of new hires; and putting a stop to deportations.
Georgia was one of five states last year that passed tough laws targeting illegal immigration.
It's not clear how many people will show up for Tuesday's rally. A May Day demonstration last year drew about 1,000 people.
The groups are instructing participants to wear white T-shirts and to bring trash bags to clean up any litter generated by the rally.